AMD is the leading cause of legal blindness in industrialized countries. It has two forms, atrophic and exudative, and a multifactorial pathogenesis. To cope with the ever-increasing incidence of AMD, retinal specialists resort to three strategies: primary prevention, patient management in clinical practice and prospective medical research aimed at finding new therapies.
Light is suspected of being a risk factor for major vision-threatening diseases. Yet an equal light exposure can unequally affect people. Multiple intricate factors are responsible for a distinct personal risk profile. The scientific quest in understanding both eye phototoxicity and individual risk profiles can set a turning point towards personalized prevention in the future.